Synthesis of two peptide mimetics as markers for chemical changes of wool's keratin during skin unhairing process.
Protein Pept Lett
; 15(4): 353-5, 2008.
Article
in En
| MEDLINE
| ID: mdl-18473946
ABSTRACT
The sheep skins unhairing process with preliminary alkaline treatment of the wool leads to two unnatural dipeptide mimetics lysinoalanine (Lys(*) - Ala) and ornithinoalanine (Orn(*)- Ala) obtaining. They are result from the keratin hydrolysis process. The changes of wool keratin make it resistant to sulphide degradation. We synthesized and characterized these unnatural dipeptides under the experimental conditions. The structures and mechanism of Lys(*) - Ala and Orn(*)- Ala obtaining were elucidated. The using of newly synthesized products as markers for control of wool's keratin changes during skin unhairing process was demonstrated. The developments have also been the result of economic and environmental pressures to meet environmental regulations.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Ornithine
/
Wool
/
Alanine
/
Dipeptides
/
Keratins
/
Lysinoalanine
Limits:
Animals
Language:
En
Journal:
Protein Pept Lett
Journal subject:
BIOQUIMICA
Year:
2008
Document type:
Article
Affiliation country: