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Optimization of small molecule agonists of the thrombopoietin (Tpo) receptor derived from a benzo[a]carbazole hit scaffold.
Marsilje, Thomas H; Alper, Phil B; Lu, Wenshuo; Mutnick, Daniel; Michellys, Pierre-Yves; He, Yun; Karanewsky, Donald S; Chow, Donald; Gerken, Andrea; Lao, Jianmin; Kim, Min-Ju; Seidel, H Martin; Tian, Shin-Shay.
Affiliation
  • Marsilje TH; Genomics Institute of the Novartis Research Foundation (GNF), San Diego, CA 92121, USA. TMarsilje@gnf.org
Bioorg Med Chem Lett ; 18(19): 5259-62, 2008 Oct 01.
Article in En | MEDLINE | ID: mdl-18783949
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Thrombopoietin / Benzene Derivatives / Carbazoles / Receptors, Thrombopoietin Type of study: Prognostic_studies Limits: Humans Language: En Journal: Bioorg Med Chem Lett Journal subject: BIOQUIMICA / QUIMICA Year: 2008 Document type: Article Affiliation country: Country of publication:
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Thrombopoietin / Benzene Derivatives / Carbazoles / Receptors, Thrombopoietin Type of study: Prognostic_studies Limits: Humans Language: En Journal: Bioorg Med Chem Lett Journal subject: BIOQUIMICA / QUIMICA Year: 2008 Document type: Article Affiliation country: Country of publication: