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SOCS3 drives proteasomal degradation of indoleamine 2,3-dioxygenase (IDO) and antagonizes IDO-dependent tolerogenesis.
Orabona, Ciriana; Pallotta, Maria T; Volpi, Claudia; Fallarino, Francesca; Vacca, Carmine; Bianchi, Roberta; Belladonna, Maria L; Fioretti, Maria C; Grohmann, Ursula; Puccetti, Paolo.
Affiliation
  • Orabona C; Department of Experimental Medicine, University of Perugia, 06126 Perugia, Italy.
Proc Natl Acad Sci U S A ; 105(52): 20828-33, 2008 Dec 30.
Article in En | MEDLINE | ID: mdl-19088199
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Dendritic Cells / Proteasome Endopeptidase Complex / Indoleamine-Pyrrole 2,3,-Dioxygenase / Suppressor of Cytokine Signaling Proteins / Ubiquitination / Immune Tolerance Type of study: Prognostic_studies Language: En Journal: Proc Natl Acad Sci U S A Year: 2008 Document type: Article Affiliation country:
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Dendritic Cells / Proteasome Endopeptidase Complex / Indoleamine-Pyrrole 2,3,-Dioxygenase / Suppressor of Cytokine Signaling Proteins / Ubiquitination / Immune Tolerance Type of study: Prognostic_studies Language: En Journal: Proc Natl Acad Sci U S A Year: 2008 Document type: Article Affiliation country: