Bifunctional DNA alkylator 1,3-bis(2-chloroethyl)-1-nitrosourea activates the ATR-Chk1 pathway independently of the mismatch repair pathway.
Mol Pharmacol
; 75(6): 1356-63, 2009 Jun.
Article
in En
| MEDLINE
| ID: mdl-19261750
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Protein Kinases
/
Carmustine
/
Protein Serine-Threonine Kinases
/
Cell Cycle Proteins
/
Antineoplastic Agents, Alkylating
/
DNA Mismatch Repair
Limits:
Humans
Language:
En
Journal:
Mol Pharmacol
Year:
2009
Document type:
Article
Affiliation country: