An antibody to IP-10 is a potent antagonist of cell migration in vitro and in vivo and does not affect disease in several animal models of inflammation.

Byrne, Fergus R; Winters, Aaron; Brankow, David; Hu, Sylvia; Juan, Todd; Steavenson, Shirley; Doellgast, George; Kuchimanchi, Kamesh; Brown, Heather; Anderson, Sharon; Smelt, Sara; Sullivan, Tim; Alcorn, Dina; Tocker, Joel; Dean, Charley; Macmaster, John; Kirchner, Jacqueline; Buys, Janet; Manoukian, Raffi; Jiao, Eric; Zou, Xiaoming; Campanella, Gabriele S; Siu, Gerald

Byrne, Fergus R; Winters, Aaron; Brankow, David; Hu, Sylvia; Juan, Todd; Steavenson, Shirley; Doellgast, George; Kuchimanchi, Kamesh; Brown, Heather; Anderson, Sharon; Smelt, Sara; Sullivan, Tim; Alcorn, Dina; Tocker, Joel; Dean, Charley; Macmaster, John; Kirchner, Jacqueline; Buys, Janet; Manoukian, Raffi; Jiao, Eric; Zou, Xiaoming; Campanella, Gabriele S; Siu, Gerald.

Affiliation

Byrne FR; Amgen Inc., Thousand Oaks, CA, USA. fbyrne@amgen.com

Autoimmunity ; 42(3): 171-82, 2009 Mar.

Article in En | MEDLINE | ID: mdl-19301198

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cell Movement / Chemokine CXCL10 / Antibodies, Monoclonal Limits: Animals Language: En Journal: Autoimmunity Journal subject: ALERGIA E IMUNOLOGIA Year: 2009 Document type: Article Affiliation country: Country of publication:

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