Cervical adenocarcinoma in situ recurring as vaginal adenocarcinoma 16 years after hysterectomy.
Int J Gynecol Pathol
; 28(3): 296-300, 2009 May.
Article
in En
| MEDLINE
| ID: mdl-19620950
ABSTRACT
We report a case in which a vaginal adenocarcinoma was discovered in a 67-year-old woman 16 years after hysterectomy for cervical adenocarcinoma in situ. Both the vaginal and cervical lesions exhibited morphologic and immunohistochemical (CDX2-positive) features of intestinal differentiation. Linear array human papillomavirus genotyping demonstrated the vaginal adenocarcinoma to contain human papillomavirus 45. We believe the vaginal adenocarcinoma to be related to the cervical adenocarcinoma in situ and to represent recurrence of this. This is an extremely rare phenomenon with, as far as we are aware, only one previous report in the literature.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Vaginal Neoplasms
/
Adenocarcinoma
/
Uterine Cervical Dysplasia
/
Uterine Cervical Neoplasms
/
Neoplasm Recurrence, Local
Limits:
Aged
/
Female
/
Humans
Language:
En
Journal:
Int J Gynecol Pathol
Year:
2009
Document type:
Article