Antifungal active triterpene glycosides from sea cucumber Holothuria scabra.
Yao Xue Xue Bao
; 44(6): 620-4, 2009 Jun.
Article
in En
| MEDLINE
| ID: mdl-19806893
ABSTRACT
To study the new antifungal active triterpene glycosides of sea cucumber Holothuria scabra. Triterpene glycosides from Holothuria scabra were separated and purified by silica gel chromatography, reversed-phase silica gel chromatography and RP-HPLC. Their structures were elucidated on the basis of spectral data and chemical evidence. Three triterpene glycosides were identified as scabraside A (1), echinoidea A (2) and holothurin A1 (3). Scabraside A (1) is a new triterpene glycoside, and compounds 2 and 3 were isolated from Holothuria scabra for the first time. They showed antifungal activities (1 < or = MIC80 < or = 16 microg mL(-1)).
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Triterpenes
/
Holothuria
/
Glycosides
/
Holothurin
/
Antifungal Agents
Limits:
Animals
Language:
En
Journal:
Yao Xue Xue Bao
Year:
2009
Document type:
Article
Affiliation country: