Prospective and descriptive study of adult dengue cases in an emergency department, in Martinique.
Med Mal Infect
; 40(8): 480-9, 2010 Aug.
Article
in En
| MEDLINE
| ID: mdl-19951833
ABSTRACT
OBJECTIVE:
Knowing about the clinical aspects of dengue in endemic zones is essential to implementation of appropriate case management protocols and public health interventions. PATIENTS ANDMETHODS:
The authors made a 4-year prospective, observational study of dengue-infected patients admitted to the emergency department of the Fort-de-France University Hospital.RESULTS:
Two hundred and sixty-three male and 297 female patients were included. The median age was 37 years (range 14-91). The diagnosis was based on a positive RT-PCR (463 patients) or on the presence of specific IgM (97 patients). Two hundred and seventy-seven patients (49.5%) presented with dengue fever without complications. According to WHO criteria, 95 patients (17%) developed plasma leakage, including 39 patients (7%) diagnosed with DHF, and 10 (1.8%) diagnosed with DSS. Among the other patients without plasma leakage, 84 (15%) had isolated thrombocytopenia, 14 (2.5%) had internal bleeding, and 90 (16%) had unusual manifestations. Seven patients died (1.3%) fulminant hepatitis (two), myocarditis (one), encephalitis (one), acute respiratory failure (one), gangrenous cholecystitis (one), and post-traumatic intracranial hemorrhage (one). The other patients recovered. Seven patients were pregnant (1.3%) from 6 to 27 weeks of amenorrhea and carried their pregnancy to term without complications.CONCLUSION:
With this experience, we were able to develop appropriate case management protocols for patients during dengue epidemics.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Dengue
Type of study:
Diagnostic_studies
/
Guideline
/
Observational_studies
/
Risk_factors_studies
Limits:
Adolescent
/
Adult
/
Aged
/
Aged80
/
Female
/
Humans
/
Male
/
Middle aged
Country/Region as subject:
Caribe
/
Martinica
Language:
En
Journal:
Med Mal Infect
Year:
2010
Document type:
Article
Affiliation country: