HIV and bone mineral density.
Curr Opin Infect Dis
; 23(1): 1-8, 2010 Feb.
Article
in En
| MEDLINE
| ID: mdl-20010102
ABSTRACT
PURPOSE OF REVIEW This review details the clinical aspects and pathogenesis of low bone mineral density (BMD) in HIV, discusses broad management issues and outlines areas in which our understanding of this condition is incomplete. RECENT FINDINGS:
Low BMD is prevalent in HIV-infected patients, with traditional risk factors, HIV infection and exposure to antiretroviral therapy all contributing. The role of specific antiretrovirals in the development of low BMD remains controversial, but most changes arise at either antiretroviral therapy initiation or switch.SUMMARY:
Further research is needed to clarify mechanisms underlying low BMD in HIV, whether low BMD will translate to increased fractures and to determine the correct therapeutic approach to low BMD in HIV, particularly in younger HIV-infected patients.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Bone Diseases, Metabolic
/
HIV Infections
Type of study:
Risk_factors_studies
Limits:
Female
/
Humans
/
Male
Language:
En
Journal:
Curr Opin Infect Dis
Journal subject:
DOENCAS TRANSMISSIVEIS
Year:
2010
Document type:
Article
Affiliation country: