Age-related differences in prostaglandin E2 synthesis by equine cartilage explants and synoviocytes.
J Vet Pharmacol Ther
; 33(3): 268-76, 2010 Jun 01.
Article
in En
| MEDLINE
| ID: mdl-20557444
ABSTRACT
Time- and concentration-related actions of lipopolysaccharide (LPS) on the synthesis of prostaglandin E(2) (PGE(2)) were investigated in cartilage explants and synoviocytes harvested from 3 age groups of horses, all with clinically normal joint function group A <10 years; group B 11-20 years and group C >20 years. Cartilage explants from group A horses were least and those from group C were most sensitive to LPS. Significant increases in PGE(2) concentration (P
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Synovial Fluid
/
Dinoprostone
/
Cartilage, Articular
Limits:
Animals
Language:
En
Journal:
J Vet Pharmacol Ther
Year:
2010
Document type:
Article
Affiliation country: