Estimation of vessel age and early diagnose of atherosclerosis in progeria syndrome by using echo-tracking.
Clin Hemorheol Microcirc
; 44(4): 297-301, 2010.
Article
in En
| MEDLINE
| ID: mdl-20571244
ABSTRACT
The stiffness of the arteries normally increases with age. Radiofrequency echo-tracking is a non-invasive ultrasound method which is able to detect the stiffness of the arteries, represented by the beta stiffness index. The estimation of biological age of vessels is possible on the basis of the normal age-group specific beta stiffness values. The beta stiffness index becomes higher in early stages of atherosclerosis as well, before any visible morphological changes. Hutchinson-Gilford progeria syndrome (HGPS) is rare genetic disorder resulting in accelerated aging including appearance of progressive atherosclerosis at an early age which determines the quality and term of life of these patients. Determination of vascular age and early diagnosis of atherosclerosis seems crucial. According to our knowledge, the estimation of vascular age detected with radiofrequency echo-tracking in HGPS patients, in contrast to the normal age-specific beta stiffness values, has not been published yet.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Progeria
/
Blood Vessels
/
Atherosclerosis
Type of study:
Diagnostic_studies
/
Screening_studies
Limits:
Adult
/
Child
/
Humans
/
Male
Language:
En
Journal:
Clin Hemorheol Microcirc
Journal subject:
ANGIOLOGIA
/
HEMATOLOGIA
Year:
2010
Document type:
Article
Affiliation country: