Diazepam and flunitrazepam as induction agents for cardiac surgical operations.
Acta Anaesthesiol Scand
; 21(4): 282-92, 1977.
Article
in En
| MEDLINE
| ID: mdl-20727
ABSTRACT
Diazepam and flunitrazepam were compared in equipotent doses as induction agents for premedicated patients having cardiac surgery. Both drugs caused a significant fall in arterial blood pressure, a rise in Paco2 and a fall in Pao2. There was no significant difference between the two drugs in onset time of anaesthesia, cardiovascular or respiratory depression, or quality of induction. There was also no significant difference from induction with thiopentone in these respects. Diazepam, over a 0.2 to 0.6 mg/kg range of doses showed no difference in toxicity, although induction was clinically smoother with the higher dose.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Preanesthetic Medication
/
Anti-Anxiety Agents
/
Diazepam
/
Flunitrazepam
/
Cardiac Surgical Procedures
Type of study:
Clinical_trials
Limits:
Humans
Language:
En
Journal:
Acta Anaesthesiol Scand
Year:
1977
Document type:
Article