Impact of biventricular and left ventricular pacing on hemodynamics and left ventricular dyssynchrony compared with right ventricular pacing in the early postoperative period following cardiac surgery.
Ann Fr Anesth Reanim
; 30(5): 403-9, 2011 May.
Article
in En
| MEDLINE
| ID: mdl-21481562
ABSTRACT
OBJECTIVES:
The aims of this study were to test the hypotheses that in the postoperative period following corrective surgery for congenital heart defects (i) atrio-right ventricular (RA-RV) pacing decreases cardiac output (CO) compared with right atrial (RA) pacing, (ii) atrio-biventricular (RA-BiV) and left ventricular (RA-LV) pacing improves CO compared with RA-RV pacing. STUDYDESIGN:
Prospective observational study. PATIENTS Children 0-2years of age referred for surgery of congenital heart defects were studied during intrinsic rhythm and atrial, atrio-right ventricular, atrio-left ventricular and atrio-biventricular pacing. CO, extrapolated from mean systolic aortic velocity (MSAV), and left ventricular dyssynchrony were assessed using transthoracic echocardiography.RESULTS:
RA-RV pacing induced a significant decrease in CO (MSAV 0.52±0.19m/s to 0.46±0.16m/s, p=0.01) and a significant increase in LV dyssynchrony (8.7±7.9ms to 33±21ms, p=0.001). RA-BiV pacing induced a significant increase in CO (MSAV 0.46±0.16m/s to 0.52±0.18m/s, p=0.01) and a significant decrease in LV dyssynchrony (33±21ms to 7±4ms, p=0.0003) compared with RA-RV pacing. RA-LV pacing induced a significant decrease in LV dyssynchrony (33±21ms to 9±7ms, p=0.0007) without a significant improvement of CO compared with RA-RV pacing.CONCLUSIONS:
RA-BiV pacing improves CO compared with RA-RV pacing in the early postoperative period following pediatric cardiac surgery. This improvement is related to a reduction in left ventricular dyssynchrony.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Cardiac Pacing, Artificial
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Ventricular Function, Right
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Ventricular Dysfunction, Left
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Cardiac Surgical Procedures
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Hemodynamics
Type of study:
Observational_studies
Limits:
Female
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Humans
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Infant
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Male
/
Newborn
Language:
En
Journal:
Ann Fr Anesth Reanim
Year:
2011
Document type:
Article
Affiliation country: