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Imatinib elicited a favorable response in a dog with a mast cell tumor carrying a c-kit c.1523A>T mutation via suppression of constitutive KIT activation.
Yamada, Osamu; Kobayashi, Masato; Sugisaki, Osamu; Ishii, Noriko; Ito, Keita; Kuroki, Shiori; Sasaki, Yu; Isotani, Mayu; Ono, Kenichiro; Washizu, Tsukimi; Bonkobara, Makoto.
Affiliation
  • Yamada O; Department of Veterinary Clinical Pathology, Nippon Veterinary and Life Science University, 1-7-1 Kyonan-cho, Musashino-shi, Tokyo 180-8602, Japan.
Vet Immunol Immunopathol ; 142(1-2): 101-6, 2011 Jul 15.
Article in En | MEDLINE | ID: mdl-21561667
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Piperazines / Pyrimidines / Proto-Oncogene Proteins c-kit / Polymorphism, Single Nucleotide / Dog Diseases / Mastocytoma, Skin / Antineoplastic Agents Type of study: Prognostic_studies Limits: Animals Language: En Journal: Vet Immunol Immunopathol Year: 2011 Document type: Article Affiliation country: Country of publication:
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Piperazines / Pyrimidines / Proto-Oncogene Proteins c-kit / Polymorphism, Single Nucleotide / Dog Diseases / Mastocytoma, Skin / Antineoplastic Agents Type of study: Prognostic_studies Limits: Animals Language: En Journal: Vet Immunol Immunopathol Year: 2011 Document type: Article Affiliation country: Country of publication: