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Hepatic nuclear factor 1alpha (HNF1alpha) dysfunction down-regulates X-box-binding protein 1 (XBP1) and sensitizes beta-cells to endoplasmic reticulum stress.
Kirkpatrick, Clare L; Wiederkehr, Andreas; Baquié, Mathurin; Akhmedov, Dmitry; Wang, Haiyan; Gauthier, Benoit R; Akerman, Ildem; Ishihara, Hisamitsu; Ferrer, Jorge; Wollheim, Claes B.
Affiliation
  • Kirkpatrick CL; Department of Cell Physiology and Metabolism, Centre Médical Universitaire, Université de Genève, 1 Rue Michel-Servet, 1211 Genève 4, Switzerland.
J Biol Chem ; 286(37): 32300-12, 2011 Sep 16.
Article in En | MEDLINE | ID: mdl-21784843

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Transcription Factors / Down-Regulation / DNA-Binding Proteins / Insulin-Secreting Cells / Hepatocyte Nuclear Factor 1-alpha / Unfolded Protein Response Limits: Animals / Humans Language: En Journal: J Biol Chem Year: 2011 Document type: Article Affiliation country:

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Transcription Factors / Down-Regulation / DNA-Binding Proteins / Insulin-Secreting Cells / Hepatocyte Nuclear Factor 1-alpha / Unfolded Protein Response Limits: Animals / Humans Language: En Journal: J Biol Chem Year: 2011 Document type: Article Affiliation country: