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Single and combination herpes simplex virus type 2 glycoprotein vaccines adjuvanted with CpG oligodeoxynucleotides or monophosphoryl lipid A exhibit differential immunity that is not correlated to protection in animal models.
Khodai, Tansi; Chappell, Debbie; Christy, Clare; Cockle, Paul; Eyles, Jim; Hammond, Daisy; Gore, Katrina; McCluskie, Michael J; Evans, Dana M; Lang, Susanne; Loudon, Peter T; Townend, Tim; Wright, Paul; West, Kate; Bright, Helen.
Affiliation
  • Khodai T; Internal Medicine Research Unit, Pfizer Research and Development, Sandwich, UK.
Clin Vaccine Immunol ; 18(10): 1702-9, 2011 Oct.
Article in En | MEDLINE | ID: mdl-21852545
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Herpes Genitalis / Viral Envelope Proteins / Adjuvants, Immunologic / Herpesvirus 2, Human / Herpesvirus Vaccines Limits: Animals Language: En Journal: Clin Vaccine Immunol Journal subject: ALERGIA E IMUNOLOGIA / TECNICAS E PROCEDIMENTOS DE LABORATORIO Year: 2011 Document type: Article Affiliation country: Country of publication:
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Herpes Genitalis / Viral Envelope Proteins / Adjuvants, Immunologic / Herpesvirus 2, Human / Herpesvirus Vaccines Limits: Animals Language: En Journal: Clin Vaccine Immunol Journal subject: ALERGIA E IMUNOLOGIA / TECNICAS E PROCEDIMENTOS DE LABORATORIO Year: 2011 Document type: Article Affiliation country: Country of publication: