Phosphoramidate ProTides of the anticancer agent FUDR successfully deliver the preformed bioactive monophosphate in cells and confer advantage over the parent nucleoside. | J Med Chem;54(20): 7247-58, 2011 Oct 27. | MEDLINE

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Phosphoramidate ProTides of the anticancer agent FUDR successfully deliver the preformed bioactive monophosphate in cells and confer advantage over the parent nucleoside.

McGuigan, Christopher; Murziani, Paola; Slusarczyk, Magdalena; Gonczy, Blanka; Vande Voorde, Johan; Liekens, Sandra; Balzarini, Jan.

Affiliation

McGuigan C; Welsh School of Pharmacy, Cardiff University, King Edward VII Avenue, Cardiff CF10 3NB, UK. mcguigan@cardiff.ac.uk

J Med Chem ; 54(20): 7247-58, 2011 Oct 27.

Article in En | MEDLINE | ID: mdl-21892829

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Organophosphorus Compounds / Prodrugs / Floxuridine / Antineoplastic Agents Limits: Humans Language: En Journal: J Med Chem Journal subject: QUIMICA Year: 2011 Document type: Article Affiliation country: Country of publication:

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Organophosphorus Compounds / Prodrugs / Floxuridine / Antineoplastic Agents Limits: Humans Language: En Journal: J Med Chem Journal subject: QUIMICA Year: 2011 Document type: Article Affiliation country: Country of publication: