Wiring the oncogenic circuitry: Pin1 unleashes mutant p53.
Oncotarget
; 2(9): 654-6, 2011 Sep.
Article
in En
| MEDLINE
| ID: mdl-21926448
ABSTRACT
Unlike several tumor suppressor genes, whose inactivation is due to deletions or truncating mutations, TP53 is most frequently hit by missense mutations in its DNA binding domain.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Cell Transformation, Neoplastic
/
Tumor Suppressor Protein p53
/
Peptidylprolyl Isomerase
Limits:
Animals
/
Female
/
Humans
Language:
En
Journal:
Oncotarget
Year:
2011
Document type:
Article
Affiliation country: