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Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia.
Dawson, Mark A; Prinjha, Rab K; Dittmann, Antje; Giotopoulos, George; Bantscheff, Marcus; Chan, Wai-In; Robson, Samuel C; Chung, Chun-wa; Hopf, Carsten; Savitski, Mikhail M; Huthmacher, Carola; Gudgin, Emma; Lugo, Dave; Beinke, Soren; Chapman, Trevor D; Roberts, Emma J; Soden, Peter E; Auger, Kurt R; Mirguet, Olivier; Doehner, Konstanze; Delwel, Ruud; Burnett, Alan K; Jeffrey, Phillip; Drewes, Gerard; Lee, Kevin; Huntly, Brian J P; Kouzarides, Tony.
Affiliation
  • Dawson MA; Department of Haematology, Cambridge Institute for Medical Research and Addenbrookes Hospital, University of Cambridge, Cambridge CB2 0XY, UK.
Nature ; 478(7370): 529-33, 2011 Oct 02.
Article in En | MEDLINE | ID: mdl-21964340
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Transcription Factors / Chromatin / Leukemia, Myeloid, Acute / Oncogene Proteins, Fusion / Myeloid-Lymphoid Leukemia Protein Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Nature Year: 2011 Document type: Article Affiliation country: Country of publication:
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Transcription Factors / Chromatin / Leukemia, Myeloid, Acute / Oncogene Proteins, Fusion / Myeloid-Lymphoid Leukemia Protein Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Nature Year: 2011 Document type: Article Affiliation country: Country of publication: