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AAV-mediated gene transfer in the perinatal period results in expression of FVII at levels that protect against fatal spontaneous hemorrhage.
Binny, Christopher; McIntosh, Jenny; Della Peruta, Marco; Kymalainen, Hanna; Tuddenham, Edward G D; Buckley, Suzanne M K; Waddington, Simon N; McVey, John H; Spence, Yunyu; Morton, Christopher L; Thrasher, Adrian J; Gray, John T; Castellino, Francis J; Tarantal, Alice F; Davidoff, Andrew M; Nathwani, Amit C.
Affiliation
  • Binny C; University College London Cancer Institute, London, UK.
Blood ; 119(4): 957-66, 2012 Jan 26.
Article in En | MEDLINE | ID: mdl-22134170
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Factor VII / Genetic Therapy / Dependovirus / Perinatal Care / Factor VII Deficiency / Genetic Vectors / Hemorrhage Type of study: Etiology_studies / Evaluation_studies / Prognostic_studies Limits: Animals / Female / Humans / Male / Pregnancy Language: En Journal: Blood Year: 2012 Document type: Article Affiliation country:
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Factor VII / Genetic Therapy / Dependovirus / Perinatal Care / Factor VII Deficiency / Genetic Vectors / Hemorrhage Type of study: Etiology_studies / Evaluation_studies / Prognostic_studies Limits: Animals / Female / Humans / Male / Pregnancy Language: En Journal: Blood Year: 2012 Document type: Article Affiliation country: