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Aspirin inhibits mTOR signaling, activates AMP-activated protein kinase, and induces autophagy in colorectal cancer cells.
Din, Farhat V N; Valanciute, Asta; Houde, Vanessa P; Zibrova, Daria; Green, Kevin A; Sakamoto, Kei; Alessi, Dario R; Dunlop, Malcolm G.
Affiliation
  • Din FV; Colon Cancer Genetics Group and Academic Coloproctology, Institute of Genetics and Molecular Medicine, University of Edinburgh and Medical Research Council Human Genetics Unit, Western General Hospital Edinburgh, United Kingdom. Farhat.Din@igmm.ed.ac.uk
Gastroenterology ; 142(7): 1504-15.e3, 2012 Jun.
Article in En | MEDLINE | ID: mdl-22406476
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Autophagy / Colorectal Neoplasms / Signal Transduction / Anti-Inflammatory Agents, Non-Steroidal / Aspirin / AMP-Activated Protein Kinases / TOR Serine-Threonine Kinases Limits: Animals / Female / Humans Language: En Journal: Gastroenterology Year: 2012 Document type: Article Affiliation country:
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Autophagy / Colorectal Neoplasms / Signal Transduction / Anti-Inflammatory Agents, Non-Steroidal / Aspirin / AMP-Activated Protein Kinases / TOR Serine-Threonine Kinases Limits: Animals / Female / Humans Language: En Journal: Gastroenterology Year: 2012 Document type: Article Affiliation country: