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Design, synthesis, and pharmacological evaluation of glutamate carboxypeptidase II (GCPII) inhibitors based on thioalkylbenzoic acid scaffolds.
Stoermer, Doris; Vitharana, Dilrukshi; Hin, Niyada; Delahanty, Greg; Duvall, Bridget; Ferraris, Dana V; Grella, Brian S; Hoover, Randall; Rojas, Camilo; Shanholtz, Megan K; Smith, Kyle P; Stathis, Marigo; Wu, Ying; Wozniak, Krystyna M; Slusher, Barbara S; Tsukamoto, Takashi.
Affiliation
  • Stoermer D; Eisai Inc., Baltimore, Maryland 21224, United States.
J Med Chem ; 55(12): 5922-32, 2012 Jun 28.
Article in En | MEDLINE | ID: mdl-22642259
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Benzoates / Drug Design / Glutamate Carboxypeptidase II / Enzyme Inhibitors Limits: Animals / Humans Language: En Journal: J Med Chem Journal subject: QUIMICA Year: 2012 Document type: Article Affiliation country: Country of publication:
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Benzoates / Drug Design / Glutamate Carboxypeptidase II / Enzyme Inhibitors Limits: Animals / Humans Language: En Journal: J Med Chem Journal subject: QUIMICA Year: 2012 Document type: Article Affiliation country: Country of publication: