Pharmacogenomics knowledge for personalized medicine.
Clin Pharmacol Ther
; 92(4): 414-7, 2012 Oct.
Article
in En
| MEDLINE
| ID: mdl-22992668
ABSTRACT
The Pharmacogenomics Knowledgebase (PharmGKB) is a resource that collects, curates, and disseminates information about the impact of human genetic variation on drug responses. It provides clinically relevant information, including dosing guidelines, annotated drug labels, and potentially actionable gene-drug associations and genotype-phenotype relationships. Curators assign levels of evidence to variant-drug associations using well-defined criteria based on careful literature review. Thus, PharmGKB is a useful source of high-quality information supporting personalized medicine-implementation projects.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Pharmacogenetics
/
Databases, Genetic
/
Knowledge Bases
/
Precision Medicine
Type of study:
Guideline
/
Prognostic_studies
Limits:
Humans
Language:
En
Journal:
Clin Pharmacol Ther
Year:
2012
Document type:
Article
Affiliation country: