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Discovery and characterization of AZD9272 and AZD6538-Two novel mGluR5 negative allosteric modulators selected for clinical development.
Raboisson, Patrick; Breitholtz-Emanuelsson, Anna; Dahllöf, Henrik; Edwards, Louise; Heaton, William L; Isaac, Methvin; Jarvie, Keith; Kers, Annika; Minidis, Alexander B E; Nordmark, Anna; Sheehan, Susan M; Slassi, Abdelmalik; Ström, Peter; Terelius, Ylva; Wensbo, David; Wilson, Julie M; Xin, Tao; McLeod, Donald A.
Affiliation
  • Raboisson P; AstraZeneca R&D, Södertälje S-15185, Sweden. patrick.raboisson.1@gmail.com
Bioorg Med Chem Lett ; 22(22): 6974-9, 2012 Nov 15.
Article in En | MEDLINE | ID: mdl-23046966
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Oxadiazoles / Pyridines / Receptors, Metabotropic Glutamate Limits: Animals / Humans / Male Language: En Journal: Bioorg Med Chem Lett Journal subject: BIOQUIMICA / QUIMICA Year: 2012 Document type: Article Affiliation country: Country of publication:
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Oxadiazoles / Pyridines / Receptors, Metabotropic Glutamate Limits: Animals / Humans / Male Language: En Journal: Bioorg Med Chem Lett Journal subject: BIOQUIMICA / QUIMICA Year: 2012 Document type: Article Affiliation country: Country of publication: