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Administration of anti-CD25 mAb leads to impaired α-galactosylceramide-mediated induction of IFN-γ production in a murine model.
Rosalia, Rodney A; Stepánek, Ivan; Polláková, Veronika; Símová, Jana; Bieblová, Jana; Indrová, Marie; Moravcová, Simona; Pribylová, Hana; Bontkes, Hetty J; Bubeník, Jan; Sparwasser, Tim; Reinis, Milan.
Affiliation
  • Rosalia RA; Department of Tumour Immunology of the Institute of Molecular Genetics, v. v. i., Academy of Sciences of the Czech Republic, Prague 4, Czech Republic.
Immunobiology ; 218(6): 851-9, 2013 Jun.
Article in En | MEDLINE | ID: mdl-23182710
Subject(s)
Antibodies, Monoclonal/pharmacology; Antineoplastic Combined Chemotherapy Protocols/therapeutic use; Galactosylceramides/pharmacology; Interferon-gamma/immunology; Interleukin-2 Receptor alpha Subunit/immunology; Natural Killer T-Cells/drug effects; Neoplasms, Experimental/drug therapy; Animals; Antibodies, Monoclonal/administration & dosage; Antibodies, Monoclonal/immunology; Antigens, CD1d/immunology; Antigens, CD1d/metabolism; Cell Line, Tumor; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Forkhead Transcription Factors/immunology; Forkhead Transcription Factors/metabolism; Galactosylceramides/administration & dosage; Galactosylceramides/immunology; Gene Expression/drug effects; Gene Expression/immunology; Heparin-binding EGF-like Growth Factor; Intercellular Signaling Peptides and Proteins/genetics; Intercellular Signaling Peptides and Proteins/immunology; Intercellular Signaling Peptides and Proteins/metabolism; Interferon-gamma/genetics; Interferon-gamma/metabolism; Interleukin-2 Receptor alpha Subunit/metabolism; Interleukin-4/genetics; Interleukin-4/immunology; Interleukin-4/metabolism; Kaplan-Meier Estimate; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Natural Killer T-Cells/immunology; Natural Killer T-Cells/metabolism; Neoplasms, Experimental/immunology; Neoplasms, Experimental/pathology; Reverse Transcriptase Polymerase Chain Reaction; T-Lymphocytes, Regulatory/drug effects; T-Lymphocytes, Regulatory/immunology; T-Lymphocytes, Regulatory/metabolism; Tumor Burden/drug effects; Tumor Burden/immunology
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Antineoplastic Combined Chemotherapy Protocols / Interferon-gamma / Interleukin-2 Receptor alpha Subunit / Natural Killer T-Cells / Galactosylceramides / Antibodies, Monoclonal / Neoplasms, Experimental Type of study: Prognostic_studies Language: En Journal: Immunobiology Year: 2013 Document type: Article Affiliation country: Country of publication:
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Antineoplastic Combined Chemotherapy Protocols / Interferon-gamma / Interleukin-2 Receptor alpha Subunit / Natural Killer T-Cells / Galactosylceramides / Antibodies, Monoclonal / Neoplasms, Experimental Type of study: Prognostic_studies Language: En Journal: Immunobiology Year: 2013 Document type: Article Affiliation country: Country of publication: