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G protein-coupled receptor-mediated activation of p110ß by Gßγ is required for cellular transformation and invasiveness.
Dbouk, Hashem A; Vadas, Oscar; Shymanets, Aliaksei; Burke, John E; Salamon, Rachel S; Khalil, Bassem D; Barrett, Mathew O; Waldo, Gary L; Surve, Chinmay; Hsueh, Christine; Perisic, Olga; Harteneck, Christian; Shepherd, Peter R; Harden, T Kendall; Smrcka, Alan V; Taussig, Ronald; Bresnick, Anne R; Nürnberg, Bernd; Williams, Roger L; Backer, Jonathan M.
Affiliation
  • Dbouk HA; Department of Molecular Pharmacology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
Sci Signal ; 5(253): ra89, 2012 Dec 04.
Article in En | MEDLINE | ID: mdl-23211529
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cell Transformation, Neoplastic / Phosphatidylinositol 3-Kinases / GTP-Binding Protein beta Subunits / GTP-Binding Protein gamma Subunits / Receptors, G-Protein-Coupled / Fibroblasts / Neoplasm Proteins / Neoplasms Limits: Humans Language: En Journal: Sci Signal Journal subject: CIENCIA / FISIOLOGIA Year: 2012 Document type: Article Affiliation country:
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cell Transformation, Neoplastic / Phosphatidylinositol 3-Kinases / GTP-Binding Protein beta Subunits / GTP-Binding Protein gamma Subunits / Receptors, G-Protein-Coupled / Fibroblasts / Neoplasm Proteins / Neoplasms Limits: Humans Language: En Journal: Sci Signal Journal subject: CIENCIA / FISIOLOGIA Year: 2012 Document type: Article Affiliation country: