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Synthesis of 19-substituted geldanamycins with altered conformations and their binding to heat shock protein Hsp90.
Kitson, Russell R A; Chang, Chuan-Hsin; Xiong, Rui; Williams, Huw E L; Davis, Adrienne L; Lewis, William; Dehn, Donna L; Siegel, David; Roe, S Mark; Prodromou, Chrisostomos; Ross, David; Moody, Christopher J.
Affiliation
  • Kitson RR; School of Chemistry, University of Nottingham, University Park, Nottingham NG7 2RD, UK.
Nat Chem ; 5(4): 307-14, 2013 Apr.
Article in En | MEDLINE | ID: mdl-23511419
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Benzoquinones / HSP90 Heat-Shock Proteins / Lactams, Macrocyclic / Antibiotics, Antineoplastic Limits: Female / Humans Language: En Journal: Nat Chem Journal subject: QUIMICA Year: 2013 Document type: Article Affiliation country: Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Benzoquinones / HSP90 Heat-Shock Proteins / Lactams, Macrocyclic / Antibiotics, Antineoplastic Limits: Female / Humans Language: En Journal: Nat Chem Journal subject: QUIMICA Year: 2013 Document type: Article Affiliation country: Country of publication: