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PI3-kinase γ promotes Rap1a-mediated activation of myeloid cell integrin α4ß1, leading to tumor inflammation and growth.
Schmid, Michael C; Franco, Irene; Kang, Sang Won; Hirsch, Emilio; Quilliam, Lawrence A; Varner, Judith A.
Affiliation
  • Schmid MC; Moores Cancer Center, University of California San Diego, La Jolla, California, United States of America.
PLoS One ; 8(4): e60226, 2013.
Article in En | MEDLINE | ID: mdl-23565202

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Rap1 GTP-Binding Proteins / Myeloid Cells / Integrin alpha4beta1 / Class Ib Phosphatidylinositol 3-Kinase / Inflammation / Neoplasms Limits: Animals / Female / Humans Language: En Journal: PLoS One Journal subject: CIENCIA / MEDICINA Year: 2013 Document type: Article Affiliation country: Country of publication:

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Rap1 GTP-Binding Proteins / Myeloid Cells / Integrin alpha4beta1 / Class Ib Phosphatidylinositol 3-Kinase / Inflammation / Neoplasms Limits: Animals / Female / Humans Language: En Journal: PLoS One Journal subject: CIENCIA / MEDICINA Year: 2013 Document type: Article Affiliation country: Country of publication: