[Thrombotic thrombocytopenic purpura: do not ignore cardiac involvement]. / Purpura thrombotique thrombocytopénique: ne pas méconnaître l'atteinte cardiaque.
Rev Med Interne
; 35(4): 264-7, 2014 Apr.
Article
in Fr
| MEDLINE
| ID: mdl-23711951
ABSTRACT
INTRODUCTION:
Thrombotic thrombocytopenic purpura (TTP) is a thrombotic microangiopathy due to ADAMTS13 deficiency (a von Willebrand factor's metalloprotease) with multiple organs' involvement, one of which may be the heart. CASE REPORT We report a 29-year-old woman who presented a TTP during her last trimester of pregnancy, under the features of a HELLP syndrome. After caesarean section, cardiac involvement was revealed by chest pain, ECG changes, antero-septal hypokinesia and troponin rise. Cardiac MRI found no large-vessel ischemic heart disease and confirmed hypokinesia.CONCLUSION:
When TTP is diagnosed, cardiac involvement must be systematically investigated by ECG and troponin assay because of the risk of a cardiac arrest.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Pregnancy Complications, Cardiovascular
/
Pregnancy Complications, Hematologic
/
Purpura, Thrombotic Thrombocytopenic
Type of study:
Diagnostic_studies
/
Etiology_studies
Limits:
Adult
/
Female
/
Humans
/
Pregnancy
Language:
Fr
Journal:
Rev Med Interne
Year:
2014
Document type:
Article