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Molecular mechanism of the camptothecin resistance of Glu710Gly topoisomerase IB mutant analyzed in vitro and in silico.
Tesauro, Cinzia; Morozzo della Rocca, Blasco; Ottaviani, Alessio; Coletta, Andrea; Zuccaro, Laura; Arnò, Barbara; D'Annessa, Ilda; Fiorani, Paola; Desideri, Alessandro.
Affiliation
  • Tesauro C; Department of Biology and Interuniversity Consortium, National Institute Biostructures and Biosystems (INBB), University of Rome Tor Vergata, Via Della Ricerca Scientifica, Rome 00133 Italy. desideri@uniroma2.it.
Mol Cancer ; 12(1): 100, 2013 Sep 03.
Article in En | MEDLINE | ID: mdl-24004603
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Camptothecin / DNA Topoisomerases, Type I / Mutation, Missense / Topoisomerase I Inhibitors / Antineoplastic Agents, Phytogenic Limits: Humans Language: En Journal: Mol Cancer Journal subject: NEOPLASIAS Year: 2013 Document type: Article
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Camptothecin / DNA Topoisomerases, Type I / Mutation, Missense / Topoisomerase I Inhibitors / Antineoplastic Agents, Phytogenic Limits: Humans Language: En Journal: Mol Cancer Journal subject: NEOPLASIAS Year: 2013 Document type: Article