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A correlation between the in vitro drug toxicity of drugs to cell lines that express human P450s and their propensity to cause liver injury in humans.
Gustafsson, Frida; Foster, Alison J; Sarda, Sunil; Bridgland-Taylor, Matthew H; Kenna, J Gerry.
Affiliation
  • Gustafsson F; * Global Safety Assessment and.
Toxicol Sci ; 137(1): 189-211, 2014 Jan.
Article in En | MEDLINE | ID: mdl-24085192

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cytochrome P-450 Enzyme System / Epithelial Cells / Chemical and Drug Induced Liver Injury / Liver Type of study: Etiology_studies / Risk_factors_studies Limits: Humans Language: En Journal: Toxicol Sci Journal subject: TOXICOLOGIA Year: 2014 Document type: Article

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cytochrome P-450 Enzyme System / Epithelial Cells / Chemical and Drug Induced Liver Injury / Liver Type of study: Etiology_studies / Risk_factors_studies Limits: Humans Language: En Journal: Toxicol Sci Journal subject: TOXICOLOGIA Year: 2014 Document type: Article