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The optimization of aminooxadiazoles as orally active inhibitors of Cdc7.
Harrington, Paul E; Bourbeau, Matthew P; Fotsch, Christopher; Frohn, Michael; Pickrell, Alexander J; Reichelt, Andreas; Sham, Kelvin; Siegmund, Aaron C; Bailis, Julie M; Bush, Tammy; Escobar, Sonia; Hickman, Dean; Heller, Scott; Hsieh, Faye; Orf, Jessica N; Rong, Minqing; San Miguel, Tisha; Tan, Helming; Zalameda, Leeanne; Allen, John G.
Affiliation
  • Harrington PE; Medicinal Chemistry, Amgen Inc., One Amgen Center Drive, Thousand Oaks, CA 91320, USA. Electronic address: pharring@amgen.com.
Bioorg Med Chem Lett ; 23(23): 6396-400, 2013 Dec 01.
Article in En | MEDLINE | ID: mdl-24120542
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Oxadiazoles / Protein Serine-Threonine Kinases / Cell Cycle Proteins / Protein Kinase Inhibitors Limits: Animals Language: En Journal: Bioorg Med Chem Lett Journal subject: BIOQUIMICA / QUIMICA Year: 2013 Document type: Article
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Oxadiazoles / Protein Serine-Threonine Kinases / Cell Cycle Proteins / Protein Kinase Inhibitors Limits: Animals Language: En Journal: Bioorg Med Chem Lett Journal subject: BIOQUIMICA / QUIMICA Year: 2013 Document type: Article