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Enhanced amino acid selection in fully evolved tryptophanyl-tRNA synthetase, relative to its urzyme, requires domain motion sensed by the D1 switch, a remote dynamic packing motif.
Weinreb, Violetta; Li, Li; Chandrasekaran, Srinivas Niranj; Koehl, Patrice; Delarue, Marc; Carter, Charles W.
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  • Weinreb V; From the Department of Biochemistry and Biophysics, CB 7260, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599-7260.
J Biol Chem ; 289(7): 4367-76, 2014 Feb 14.
Article in En | MEDLINE | ID: mdl-24394410
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Geobacillus stearothermophilus / Bacterial Proteins / Tryptophan-tRNA Ligase Language: En Journal: J Biol Chem Year: 2014 Document type: Article Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Geobacillus stearothermophilus / Bacterial Proteins / Tryptophan-tRNA Ligase Language: En Journal: J Biol Chem Year: 2014 Document type: Article Country of publication: