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Improving the in vivo therapeutic index of siRNA polymer conjugates through increasing pH responsiveness.
Guidry, Erin N; Farand, Julie; Soheili, Arash; Parish, Craig A; Kevin, Nancy J; Pipik, Brenda; Calati, Kathleen B; Ikemoto, Nori; Waldman, Jacob H; Latham, Andrew H; Howell, Bonnie J; Leone, Anthony; Garbaccio, Robert M; Barrett, Stephanie E; Parmar, Rubina Giare; Truong, Quang T; Mao, Bing; Davies, Ian W; Colletti, Steven L; Sepp-Lorenzino, Laura.
Affiliation
  • Guidry EN; Department of Process Chemistry and ∥Department of Analytical Chemistry, Merck & Co. Inc. , , Rahway, New Jersey, United States.
Bioconjug Chem ; 25(2): 296-307, 2014 Feb 19.
Article in En | MEDLINE | ID: mdl-24409989
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Polymers / RNA, Small Interfering / Hydrogen-Ion Concentration Limits: Animals Language: En Journal: Bioconjug Chem Journal subject: BIOQUIMICA Year: 2014 Document type: Article Affiliation country:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Polymers / RNA, Small Interfering / Hydrogen-Ion Concentration Limits: Animals Language: En Journal: Bioconjug Chem Journal subject: BIOQUIMICA Year: 2014 Document type: Article Affiliation country: