Human procaspase-1 variants with decreased enzymatic activity are associated with febrile episodes and may contribute to inflammation via RIP2 and NF-&#954;B signaling.

Heymann, Michael C; Winkler, Stefan; Luksch, Hella; Flecks, Silvana; Franke, Marcus; Ruß, Susanne; Ozen, Seza; Yilmaz, Engin; Klein, Christoph; Kallinich, Tilmann; Lindemann, Dirk; Brenner, Sebastian; Ganser, Gerd; Roesler, Joachim; Rösen-Wolff, Angela; Hofmann, Sigrun R

Human procaspase-1 variants with decreased enzymatic activity are associated with febrile episodes and may contribute to inflammation via RIP2 and NF-κB signaling.

Heymann, Michael C; Winkler, Stefan; Luksch, Hella; Flecks, Silvana; Franke, Marcus; Ruß, Susanne; Ozen, Seza; Yilmaz, Engin; Klein, Christoph; Kallinich, Tilmann; Lindemann, Dirk; Brenner, Sebastian; Ganser, Gerd; Roesler, Joachim; Rösen-Wolff, Angela; Hofmann, Sigrun R.

Affiliation

Heymann MC; Klinik und Poliklinik für Kinder- und Jugendmedizin, Medizinische Fakultät der Technischen Universität Dresden, 01307 Dresden, Germany;

J Immunol ; 192(9): 4379-85, 2014 May 01.

Article in En | MEDLINE | ID: mdl-24706726

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: NF-kappa B / Caspase 1 / Receptor-Interacting Protein Serine-Threonine Kinase 2 / Fever / Inflammation Type of study: Prognostic_studies / Risk_factors_studies Limits: Humans Language: En Journal: J Immunol Year: 2014 Document type: Article

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