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Synthesis and structure-activity relationship of trisubstituted thiazoles as Cdc7 kinase inhibitors.
Reichelt, Andreas; Bailis, Julie M; Bartberger, Michael D; Yao, Guomin; Shu, Hong; Kaller, Matthew R; Allen, John G; Weidner, Margaret F; Keegan, Kathleen S; Dao, Jennifer H.
Affiliation
  • Reichelt A; Medicinal Chemistry, Amgen, Inc., One Amgen Center Drive, Thousand Oaks, CA 91320, USA. Electronic address: Andreas.Reichelt@amgen.com.
  • Bailis JM; Oncology Research, Amgen, Inc., 1201 Amgen Court West, Seattle, WA 98119, USA.
  • Bartberger MD; Molecular Structure and Characterization, Amgen, Inc., One Amgen Center Drive, Thousand Oaks, CA 91320, USA.
  • Yao G; Medicinal Chemistry, Amgen, Inc., One Amgen Center Drive, Thousand Oaks, CA 91320, USA.
  • Shu H; Medicinal Chemistry, Amgen, Inc., One Amgen Center Drive, Thousand Oaks, CA 91320, USA.
  • Kaller MR; Medicinal Chemistry, Amgen, Inc., One Amgen Center Drive, Thousand Oaks, CA 91320, USA.
  • Allen JG; Medicinal Chemistry, Amgen, Inc., One Amgen Center Drive, Thousand Oaks, CA 91320, USA.
  • Weidner MF; Oncology Research, Amgen, Inc., 1201 Amgen Court West, Seattle, WA 98119, USA.
  • Keegan KS; Oncology Research, Amgen, Inc., 1201 Amgen Court West, Seattle, WA 98119, USA.
  • Dao JH; Molecular Structure and Characterization, Amgen, Inc., One Amgen Center Drive, Thousand Oaks, CA 91320, USA.
Eur J Med Chem ; 80: 364-82, 2014 Jun 10.
Article in En | MEDLINE | ID: mdl-24793884

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Thiazoles / Protein Serine-Threonine Kinases / Cell Cycle Proteins / Protein Kinase Inhibitors Type of study: Prognostic_studies Limits: Animals / Female / Humans / Male Language: En Journal: Eur J Med Chem Year: 2014 Document type: Article

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Thiazoles / Protein Serine-Threonine Kinases / Cell Cycle Proteins / Protein Kinase Inhibitors Type of study: Prognostic_studies Limits: Animals / Female / Humans / Male Language: En Journal: Eur J Med Chem Year: 2014 Document type: Article