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Sex: how malaria parasites get turned on.
Ankarklev, Johan; Brancucci, Nicolas M B; Goldowitz, Ilana; Mantel, Pierre-Yves; Marti, Matthias.
Affiliation
  • Ankarklev J; Harvard School of Public Health, Department of Immunology and Infectious Diseases, 665 Huntington Ave, Boston, MA 02115, USA.
  • Brancucci NM; Harvard School of Public Health, Department of Immunology and Infectious Diseases, 665 Huntington Ave, Boston, MA 02115, USA.
  • Goldowitz I; Harvard School of Public Health, Department of Immunology and Infectious Diseases, 665 Huntington Ave, Boston, MA 02115, USA.
  • Mantel PY; Harvard School of Public Health, Department of Immunology and Infectious Diseases, 665 Huntington Ave, Boston, MA 02115, USA.
  • Marti M; Harvard School of Public Health, Department of Immunology and Infectious Diseases, 665 Huntington Ave, Boston, MA 02115, USA. Electronic address: mmarti@hsph.harvard.edu.
Curr Biol ; 24(9): R368-70, 2014 May 05.
Article in En | MEDLINE | ID: mdl-24801188
ABSTRACT
The mechanisms underlying sexual stage switching in Plasmodium spp. have hitherto remained a mystery. However, two recent studies have revealed that an apicomplexan-specific DNA-binding protein is essential for the initiation of this cell fate decision, ultimately providing the malaria community with a novel and important tool in the battle to prevent malaria transmission.
Subject(s)

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Parasites / Plasmodium berghei / Plasmodium falciparum / Transcription, Genetic / Gene Expression Regulation / Sexual Development / Germ Cells / Malaria Limits: Animals Language: En Journal: Curr Biol Journal subject: BIOLOGIA Year: 2014 Document type: Article Affiliation country:

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Parasites / Plasmodium berghei / Plasmodium falciparum / Transcription, Genetic / Gene Expression Regulation / Sexual Development / Germ Cells / Malaria Limits: Animals Language: En Journal: Curr Biol Journal subject: BIOLOGIA Year: 2014 Document type: Article Affiliation country: