Preparation and enantioselectivity binding studies of a new chiral cobalt(II)porphyrin-Tröger's base conjugate.
Chirality
; 26(8): 361-7, 2014 Aug.
Article
in En
| MEDLINE
| ID: mdl-24819313
ABSTRACT
A new bis[cobalt(II)porphyrin]-Tröger's base conjugate was studied as a potential receptor for methyl esters of several amino acids. The conjugate was prepared as racemate, and then resolved via preparative high-performance liquid chromatography (HPLC) on a chiral column. The high affinity to lysine, histidine, and proline methyl esters was found by complexation studies followed by UV-Vis spectroscopy. The studies of pure enantiomers, followed by UV-Vis and electronic circular dichroism spectroscopy, revealed the highest enantioselectivity for lysine methyl ester.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Language:
En
Journal:
Chirality
Journal subject:
BIOLOGIA MOLECULAR
/
QUIMICA
Year:
2014
Document type:
Article
Affiliation country: