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A series of potent CREBBP bromodomain ligands reveals an induced-fit pocket stabilized by a cation-π interaction.
Rooney, Timothy P C; Filippakopoulos, Panagis; Fedorov, Oleg; Picaud, Sarah; Cortopassi, Wilian A; Hay, Duncan A; Martin, Sarah; Tumber, Anthony; Rogers, Catherine M; Philpott, Martin; Wang, Minghua; Thompson, Amber L; Heightman, Tom D; Pryde, David C; Cook, Andrew; Paton, Robert S; Müller, Susanne; Knapp, Stefan; Brennan, Paul E; Conway, Stuart J.
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  • Rooney TP; Department of Chemistry, Chemistry Research Laboratory, University of Oxford, Mansfield Road, Oxford, OX1 3TA (UK) http://conway.chem.ox.ac.uk/
Angew Chem Int Ed Engl ; 53(24): 6126-30, 2014 Jun 10.
Article in En | MEDLINE | ID: mdl-24821300
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cations / CREB-Binding Protein / Epigenomics Language: En Journal: Angew Chem Int Ed Engl Year: 2014 Document type: Article Country of publication:
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cations / CREB-Binding Protein / Epigenomics Language: En Journal: Angew Chem Int Ed Engl Year: 2014 Document type: Article Country of publication: