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Characterization of asparagine 330 deamidation in an Fc-fragment of IgG1 using cation exchange chromatography and peptide mapping.
Zhang, Yonghua Taylor; Hu, Jennifer; Pace, Amanda L; Wong, Rita; Wang, Y John; Kao, Yung-Hsiang.
Affiliation
  • Zhang YT; Department of Protein Analytical Chemistry, Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA. Electronic address: yonghuaz@gene.com.
  • Hu J; Department of Protein Analytical Chemistry, Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA.
  • Pace AL; Late Stage Pharmaceutical Development, Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA.
  • Wong R; Late Stage Pharmaceutical Development, Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA.
  • Wang YJ; Late Stage Pharmaceutical Development, Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA.
  • Kao YH; Late Stage Pharmaceutical Development, Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA.
J Chromatogr B Analyt Technol Biomed Life Sci ; 965: 65-71, 2014 Aug 15.
Article in En | MEDLINE | ID: mdl-24999246
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Asparagine / Peptide Mapping / Immunoglobulin G / Immunoglobulin Fc Fragments / Chromatography, Ion Exchange Limits: Animals Language: En Journal: J Chromatogr B Analyt Technol Biomed Life Sci Journal subject: ENGENHARIA BIOMEDICA Year: 2014 Document type: Article
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Asparagine / Peptide Mapping / Immunoglobulin G / Immunoglobulin Fc Fragments / Chromatography, Ion Exchange Limits: Animals Language: En Journal: J Chromatogr B Analyt Technol Biomed Life Sci Journal subject: ENGENHARIA BIOMEDICA Year: 2014 Document type: Article