[Casual diagnosis of Gitelman's syndrome]. / Diagnóstico casual de un síndrome de Gitelman.
Semergen
; 40(7): e95-8, 2014 Oct.
Article
in Es
| MEDLINE
| ID: mdl-25016940
ABSTRACT
Gitelman's syndrome is a renal tubule disease of recessive autosomal inheritance in which the fundamental alteration is found in the distal tubule, specifically at the level of the Na/Cl cotransporter, is sensitive to thiazides, and coded in chromosome 16q. It is characterised by a metabolic alkalosis with normal blood pressure, hypokalaemia, as well as hypomagnesaemia and hypocalciuria, which separate it from Bartter's syndrome. Its diagnosis can be delayed up to the adult age, as patients may remain asymptomatic for long periods of time. The treatment consists of oral supplements of potassium and magnesium, and the use of potassium-sparing diuretics and indomethacin has also been described.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Bartter Syndrome
/
Gitelman Syndrome
/
Hypokalemia
Type of study:
Diagnostic_studies
Limits:
Adult
/
Female
/
Humans
Language:
Es
Journal:
Semergen
Year:
2014
Document type:
Article