The relationship between age and minimum alveolar concentration of sevoflurane for maintaining bispectral index below 50 in children.
Anaesthesia
; 70(3): 318-22, 2015 Mar.
Article
in En
| MEDLINE
| ID: mdl-25271891
ABSTRACT
We evaluated the minimum alveolar concentration of sevoflurane required to maintain the bispectral index below 50 in children. We studied 55 children, divided into 1-year-old, 2- to 4-year-old and 5- to 9-year-old groups and used Dixon's up-and-down method and probit analysis. In the 1-year-old group, the bispectral index values remained above 50, with the end-tidal sevoflurane concentration reaching 4.0% or higher. The minimum alveolar concentration of sevoflurane for maintaining the bispectral index below 50 was significantly higher in the 2- to 4-year-old group (2.33%, 95% CI 2.25-2.57) than in the 5- to 9-year-old group (2.10%, 95% CI 1.94-2.25; p = 0.005). We conclude that assessing the depth of anaesthesia using bispectral index is unreliable in children aged < 2 years anaesthetised with sevoflurane.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Pulmonary Alveoli
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Monitoring, Intraoperative
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Anesthetics, Inhalation
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Electroencephalography
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Methyl Ethers
Limits:
Child
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Child, preschool
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Female
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Humans
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Infant
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Male
Language:
En
Journal:
Anaesthesia
Year:
2015
Document type:
Article
Affiliation country: