The development of the disease activity score (DAS) and the disease activity score using 28 joint counts (DAS28).
Clin Exp Rheumatol
; 32(5 Suppl 85): S-65-74, 2014.
Article
in En
| MEDLINE
| ID: mdl-25365092
ABSTRACT
In rheumatoid arthritis, disease activity cannot be measured using a single variable. The Disease Activity Score (DAS) has been developed as a quantitative index to be able to measure, study and manage disease activity in RA in daily clinical practice, clinical trials, and long term observational studies. The DAS is a continuous measure of RA disease activity that combines information from swollen joints, tender joints, acute phase response and patient self-report of general health. Cut points were developed to classify patients in remission, as well as low, moderate, and severe disease activity in the 1990s. DAS-based EULAR response criteria were primarily developed to be used in clinical trials to classify individual patients as non-, moderate, or good responders, depending on the magnitude of change and absolute level of disease activity at the conclusion of the test.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Arthritis, Rheumatoid
/
Rheumatology
/
Joints
Type of study:
Observational_studies
/
Prognostic_studies
Aspects:
Patient_preference
Limits:
Humans
Language:
En
Journal:
Clin Exp Rheumatol
Year:
2014
Document type:
Article
Affiliation country: