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The Hedgehog pathway effector smoothened exhibits signaling competency in the absence of ciliary accumulation.
Fan, Chih-Wei; Chen, Baozhi; Franco, Irene; Lu, Jianming; Shi, Heping; Wei, Shuguang; Wang, Changguang; Wu, Xiaofeng; Tang, Wei; Roth, Michael G; Williams, Noelle S; Hirsch, Emilio; Chen, Chuo; Lum, Lawrence.
Affiliation
  • Fan CW; Department of Cell Biology, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390, USA.
  • Chen B; Department of Cell Biology, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390, USA.
  • Franco I; Molecular Biotechnology Center, Department of Molecular Biotechnology and Health Sciences, University of Torino, 10126 Torino, Italy.
  • Lu J; Department of Biochemistry, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390, USA.
  • Shi H; Department of Biochemistry, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390, USA.
  • Wei S; Department of Biochemistry, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390, USA.
  • Wang C; Department of Biochemistry, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390, USA.
  • Wu X; Department of Cell Biology, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390, USA.
  • Tang W; Department of Cell Biology, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390, USA.
  • Roth MG; Department of Biochemistry, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390, USA.
  • Williams NS; Department of Biochemistry, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390, USA.
  • Hirsch E; Molecular Biotechnology Center, Department of Molecular Biotechnology and Health Sciences, University of Torino, 10126 Torino, Italy.
  • Chen C; Department of Biochemistry, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390, USA.
  • Lum L; Department of Cell Biology, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390, USA. Electronic address: lawrence.lum@utsouthwestern.edu.
Chem Biol ; 21(12): 1680-9, 2014 Dec 18.
Article in En | MEDLINE | ID: mdl-25484239

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Signal Transduction / Receptors, G-Protein-Coupled / Hedgehog Proteins Limits: Animals / Humans Language: En Journal: Chem Biol Journal subject: BIOLOGIA / BIOQUIMICA / QUIMICA Year: 2014 Document type: Article Affiliation country:

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Signal Transduction / Receptors, G-Protein-Coupled / Hedgehog Proteins Limits: Animals / Humans Language: En Journal: Chem Biol Journal subject: BIOLOGIA / BIOQUIMICA / QUIMICA Year: 2014 Document type: Article Affiliation country: