Bilateral thalamic stimulation induces insomnia in patients treated for intractable tremor.
Sleep
; 38(3): 473-8, 2015 Mar 01.
Article
in En
| MEDLINE
| ID: mdl-25515098
ABSTRACT
STUDY OBJECTIVES:
To explore the influence of acute bilateral ventral intermediate thalamic nucleus (VIM) stimulation on sleep.DESIGN:
Three consecutive full-night polysomnography recordings were made in the laboratory. After the habituation night, a random order for night ON-stim and OFF-stim was applied for the second and third nights.SETTING:
Sleep disorders unit of a university hospital. PATIENTS Eleven patients with bilateral stimulation of the ventral intermediate nucleus of the thalamus (VIM) for drug-resistant tremor. MEASUREMENTS Sleep measures on polysomnography.RESULTS:
Total sleep time was reduced during night ON-stim compared to OFF- stim, as well as rapid eye movement sleep percentage while the percentage of N2 increased. Wakefulness after sleep onset time was increased.CONCLUSION:
Our results show that bilateral stimulation of the VIM nuclei reduces sleep and could be associated with insomnia.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Thalamic Nuclei
/
Tremor
/
Sleep Initiation and Maintenance Disorders
Type of study:
Clinical_trials
Limits:
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Language:
En
Journal:
Sleep
Year:
2015
Document type:
Article
Affiliation country: