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Characterization of the novel DNA gyrase inhibitor AZD0914: low resistance potential and lack of cross-resistance in Neisseria gonorrhoeae.
Alm, Richard A; Lahiri, Sushmita D; Kutschke, Amy; Otterson, Linda G; McLaughlin, Robert E; Whiteaker, James D; Lewis, Lisa A; Su, Xiaohong; Huband, Michael D; Gardner, Humphrey; Mueller, John P.
Affiliation
  • Alm RA; Infection Innovative Medicines Unit, AstraZeneca R&D Boston, Waltham, Massachusetts, USA richard.alm@astrazeneca.com sushmita.lahiri@astrazeneca.com.
  • Lahiri SD; Infection Innovative Medicines Unit, AstraZeneca R&D Boston, Waltham, Massachusetts, USA richard.alm@astrazeneca.com sushmita.lahiri@astrazeneca.com.
  • Kutschke A; Infection Innovative Medicines Unit, AstraZeneca R&D Boston, Waltham, Massachusetts, USA.
  • Otterson LG; Infection Innovative Medicines Unit, AstraZeneca R&D Boston, Waltham, Massachusetts, USA.
  • McLaughlin RE; Infection Innovative Medicines Unit, AstraZeneca R&D Boston, Waltham, Massachusetts, USA.
  • Whiteaker JD; Infection Innovative Medicines Unit, AstraZeneca R&D Boston, Waltham, Massachusetts, USA.
  • Lewis LA; UMass Medical School, Worcester, Massachusetts, USA.
  • Su X; Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, Nanjing, People's Republic of China.
  • Huband MD; Infection Innovative Medicines Unit, AstraZeneca R&D Boston, Waltham, Massachusetts, USA.
  • Gardner H; Infection Innovative Medicines Unit, AstraZeneca R&D Boston, Waltham, Massachusetts, USA.
  • Mueller JP; Infection Innovative Medicines Unit, AstraZeneca R&D Boston, Waltham, Massachusetts, USA.
Antimicrob Agents Chemother ; 59(3): 1478-86, 2015 Mar.
Article in En | MEDLINE | ID: mdl-25534723
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Spiro Compounds / Barbiturates / Topoisomerase II Inhibitors / Neisseria gonorrhoeae Type of study: Prognostic_studies Language: En Journal: Antimicrob Agents Chemother Year: 2015 Document type: Article Country of publication:
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Spiro Compounds / Barbiturates / Topoisomerase II Inhibitors / Neisseria gonorrhoeae Type of study: Prognostic_studies Language: En Journal: Antimicrob Agents Chemother Year: 2015 Document type: Article Country of publication: