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Design and synthesis of a novel series of histamine H3 receptor antagonists through a scaffold hopping strategy.
Gao, Zhongli; Hurst, William J; Hall, Daniel; Hartung, Ryan; Reynolds, William; Kang, Jiesheng; Nagorny, Raisa; Hendrix, James A; George, Pascal G.
Affiliation
  • Gao Z; LGCR SMRPD Chemical Research, Sanofi US, 153-1-130, 153 2nd Ave, Waltham, MA 02451, USA. Electronic address: zhongli.gao@sanofi.com.
  • Hurst WJ; Sanofi US, 55C-420A, 55 Corporate Drive, Bridgewater, NJ 08807, USA. Electronic address: william.hurst@sanofi.com.
  • Hall D; Sanofi US, 55C-420A, 55 Corporate Drive, Bridgewater, NJ 08807, USA.
  • Hartung R; Sanofi US, 55C-420A, 55 Corporate Drive, Bridgewater, NJ 08807, USA.
  • Reynolds W; Sanofi US, 55C-420A, 55 Corporate Drive, Bridgewater, NJ 08807, USA.
  • Kang J; Proteogenomics, Sanofi/Genzyme R&D Center, 49 New York Avenue, Framingham, MA 01701, USA.
  • Nagorny R; Sanofi US, 55C-420A, 55 Corporate Drive, Bridgewater, NJ 08807, USA.
  • Hendrix JA; Sanofi US, 55C-420A, 55 Corporate Drive, Bridgewater, NJ 08807, USA. Electronic address: jhendrix@alz.org.
  • George PG; Sanofi R&D, 1, Avenue Pierre Brossolette, Chilly-Mazarin 91385, France.
Bioorg Med Chem ; 23(3): 429-38, 2015 Feb 01.
Article in En | MEDLINE | ID: mdl-25577710
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Histamine H3 Antagonists Type of study: Prognostic_studies Limits: Animals / Female / Humans / Male Language: En Journal: Bioorg Med Chem Journal subject: BIOQUIMICA / QUIMICA Year: 2015 Document type: Article Country of publication:
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Histamine H3 Antagonists Type of study: Prognostic_studies Limits: Animals / Female / Humans / Male Language: En Journal: Bioorg Med Chem Journal subject: BIOQUIMICA / QUIMICA Year: 2015 Document type: Article Country of publication: