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Axonal regeneration. Systemic administration of epothilone B promotes axon regeneration after spinal cord injury.
Ruschel, Jörg; Hellal, Farida; Flynn, Kevin C; Dupraz, Sebastian; Elliott, David A; Tedeschi, Andrea; Bates, Margaret; Sliwinski, Christopher; Brook, Gary; Dobrindt, Kristina; Peitz, Michael; Brüstle, Oliver; Norenberg, Michael D; Blesch, Armin; Weidner, Norbert; Bunge, Mary Bartlett; Bixby, John L; Bradke, Frank.
Affiliation
  • Ruschel J; Axonal Growth and Regeneration, German Center for Neurodegenerative Diseases, Ludwig-Erhard-Allee 2, 53175 Bonn, Germany.
  • Hellal F; Axonal Growth and Regeneration, German Center for Neurodegenerative Diseases, Ludwig-Erhard-Allee 2, 53175 Bonn, Germany.
  • Flynn KC; Axonal Growth and Regeneration, German Center for Neurodegenerative Diseases, Ludwig-Erhard-Allee 2, 53175 Bonn, Germany.
  • Dupraz S; Axonal Growth and Regeneration, German Center for Neurodegenerative Diseases, Ludwig-Erhard-Allee 2, 53175 Bonn, Germany.
  • Elliott DA; Axonal Growth and Regeneration, German Center for Neurodegenerative Diseases, Ludwig-Erhard-Allee 2, 53175 Bonn, Germany.
  • Tedeschi A; Axonal Growth and Regeneration, German Center for Neurodegenerative Diseases, Ludwig-Erhard-Allee 2, 53175 Bonn, Germany.
  • Bates M; The Miami Project to Cure Paralysis, University of Miami Miller School of Medicine, 1095 Northwest 14th Terrace, Miami, FL33136, USA.
  • Sliwinski C; Spinal Cord Injury Center, Heidelberg University Hospital, Schlierbacher Landstr. 200A, 69118 Heidelberg, Germany.
  • Brook G; Institute for Neuropathology, RWTH Aachen University, Steinbergweg 20, 52074, Aachen, Germany. Jülich-Aachen Research Alliance-Translational Brain Medicine.
  • Dobrindt K; Institute of Reconstructive Neurobiology, Life&Brain Center, University of Bonn and Hertie Foundation, Sigmund-Freud-Strasse 25, 53127 Bonn, Germany.
  • Peitz M; Institute of Reconstructive Neurobiology, Life&Brain Center, University of Bonn and Hertie Foundation, Sigmund-Freud-Strasse 25, 53127 Bonn, Germany.
  • Brüstle O; Institute of Reconstructive Neurobiology, Life&Brain Center, University of Bonn and Hertie Foundation, Sigmund-Freud-Strasse 25, 53127 Bonn, Germany.
  • Norenberg MD; Departments of Pathology, Biochemistry and Molecular Biology, University of Miami School of Medicine, Miami, FL 33101, USA.
  • Blesch A; Spinal Cord Injury Center, Heidelberg University Hospital, Schlierbacher Landstr. 200A, 69118 Heidelberg, Germany.
  • Weidner N; Spinal Cord Injury Center, Heidelberg University Hospital, Schlierbacher Landstr. 200A, 69118 Heidelberg, Germany.
  • Bunge MB; The Miami Project to Cure Paralysis, University of Miami Miller School of Medicine, 1095 Northwest 14th Terrace, Miami, FL33136, USA.
  • Bixby JL; The Miami Project to Cure Paralysis, University of Miami Miller School of Medicine, 1095 Northwest 14th Terrace, Miami, FL33136, USA.
  • Bradke F; Axonal Growth and Regeneration, German Center for Neurodegenerative Diseases, Ludwig-Erhard-Allee 2, 53175 Bonn, Germany. frank.bradke@dzne.de.
Science ; 348(6232): 347-52, 2015 Apr 17.
Article in En | MEDLINE | ID: mdl-25765066

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Spinal Cord Injuries / Axons / Cicatrix / Epothilones / Tubulin Modulators / Nerve Regeneration Limits: Animals / Humans Language: En Journal: Science Year: 2015 Document type: Article Affiliation country:

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Spinal Cord Injuries / Axons / Cicatrix / Epothilones / Tubulin Modulators / Nerve Regeneration Limits: Animals / Humans Language: En Journal: Science Year: 2015 Document type: Article Affiliation country: