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Growth-factor-driven rescue to receptor tyrosine kinase (RTK) inhibitors through Akt and Erk phosphorylation in pediatric low grade astrocytoma and ependymoma.
Sie, Mariska; den Dunnen, Wilfred F A; Lourens, Harm Jan; Meeuwsen-de Boer, Tiny G J; Scherpen, Frank J G; Zomerman, Walderik W; Kampen, Kim R; Hoving, Eelco W; de Bont, Eveline S J M.
Affiliation
  • Sie M; Department of Pediatrics, Beatrix Children's Hospital, Pediatric Oncology/Hematology division, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.
  • den Dunnen WF; Department of Pathology and Medical Biology, Pathology division, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.
  • Lourens HJ; Department of Pediatrics, Beatrix Children's Hospital, Pediatric Oncology/Hematology division, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.
  • Meeuwsen-de Boer TG; Department of Pediatrics, Beatrix Children's Hospital, Pediatric Oncology/Hematology division, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.
  • Scherpen FJ; Department of Pediatrics, Beatrix Children's Hospital, Pediatric Oncology/Hematology division, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.
  • Zomerman WW; Department of Pediatrics, Beatrix Children's Hospital, Pediatric Oncology/Hematology division, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.
  • Kampen KR; Department of Pediatrics, Beatrix Children's Hospital, Pediatric Oncology/Hematology division, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.
  • Hoving EW; Department of Neurosurgery, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.
  • de Bont ES; Department of Pediatrics, Beatrix Children's Hospital, Pediatric Oncology/Hematology division, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.
PLoS One ; 10(3): e0122555, 2015.
Article in En | MEDLINE | ID: mdl-25799134
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Signal Transduction / Intercellular Signaling Peptides and Proteins / Extracellular Signal-Regulated MAP Kinases / Protein Kinase Inhibitors / Proto-Oncogene Proteins c-akt Limits: Humans Language: En Journal: PLoS One Journal subject: CIENCIA / MEDICINA Year: 2015 Document type: Article Affiliation country: Country of publication:
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Signal Transduction / Intercellular Signaling Peptides and Proteins / Extracellular Signal-Regulated MAP Kinases / Protein Kinase Inhibitors / Proto-Oncogene Proteins c-akt Limits: Humans Language: En Journal: PLoS One Journal subject: CIENCIA / MEDICINA Year: 2015 Document type: Article Affiliation country: Country of publication: