Young-age prostate cancer.
J Clin Pathol
; 68(7): 511-5, 2015 Jul.
Article
in En
| MEDLINE
| ID: mdl-25837493
ABSTRACT
Although prostate cancer is a disease of the elderly, its diagnosis is not uncommonly made in men younger than 55â
years. Both ethnic, familial and genetic factors play a role in the early onset of prostate cancer, but the biology, particularly of low-grade prostate cancers detected at young age is not well understood. Autopsy studies have shown a high prevalence of Gleason score 6 prostate cancers in men under 55â
years, but mortality of prostate cancer at this young age is almost negligible. Recently, a number of susceptibility genes such as BRCA2 and HOXB13 were reported, each with their own specific biological and histopathology features. In this review, we provide an update on the most recent findings in young-age prostate cancer.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Prostatic Neoplasms
Type of study:
Etiology_studies
/
Prevalence_studies
/
Risk_factors_studies
Limits:
Adult
/
Humans
/
Male
/
Middle aged
Language:
En
Journal:
J Clin Pathol
Year:
2015
Document type:
Article
Affiliation country: